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Appendix A: Glossary

General Terms

Collagen

A group of proteins found in connective tissue including tendons, ligaments, skin, bone, blood vessels and intervertebral discs.

Wayfinding

Act of spatial problem solving.

Heating, Ventilating, and Air Conditioning System (HVAC)

Equipment, distribution systems and terminals that provide the processes of heating, ventilating or air conditioning.

Pancreas

A glandular organ that produces several important hormones including insulin, glucagon and digestive enzymes that aid the small intestine in nutrient-absorption.

Polybrominated Diphenyl Ethers (PBDE)

Compounds used as flame retardants in a wide array of products, including building materials, electronics, furnishings, motor vehicles, airplanes, plastics, polyurethane foams and textiles.

Protozoa

Any single-celled eukaryotic (having a nucleus) organism, such as an amoeba.

Conduction

Heat transfer through physical contact with another object.

Cone Cells

Photosensitive cells in the eye used to differentiate colors and brightness in moderate and high levels of illumination.

Congeners

A class of related compounds, similar in structure and chemical properties.

Wave Amplitude

Measurement of the wave change over a single period of time.

Sarcopenia

Age related loss of skeletal muscle mass, including quality and strength.

Oxidized

Oxidative rancidity occurs during a free radical process where the double bonds of an unsaturated fat are cleaved in the presence of oxygen, relasing volatile aldehydes and ketones.

Portland Clinker

Lumps produced by sintering limestone and alumino-silicate (clay) during the cement kiln stage.

Hygrothermal

A term used to connect heat and moisture flows and their combined effect on building envelope (enclosure) performance.

Core Body Temperature (CBT)

Temperature of an organism far with the body, such as in internal organs.

Coronary Heart Disease

A heart condition caused by reduced blood flow through the coronary arteries to the heart muscle, typically resulting in chest pain or heart damage.

Plasticizers

Added during material production to impart varying degrees of elasticity.

Immunosuppressive

Any compound or substance that may impair proper immune functioning.

Safe Drinking Water Act of 1974

Passed by congress in 1974, authorizing the EPA to set national limits on contaminant levels in drinking water making it safe for human consumption. Under this program, EPA regulates public water systems that provide "piped water for human consumption" and serve at least 25 individuals or has 15 service connections.

Phosphogypsum

The byproduct of the processing of phosphate ore; mainly in the production of fertilizers.

Healthy Building Network

An organization that publishes and researches information on the sustainability of building materials and advocates environmentally friendly building materials and building policies.

Toxigenic Molds

Molds that can have a harmful effect when inhaled or ingested.

Culturable Mold

Culturable mold can be defined as mold that is alive, and will therefore grow in a culture sample, as opposed to non-culturable mold that is dead or dormant and would go undetected with culture sampling.

Curie

Unit of radioactivity corresponding to 37 billion atomic nucleus disintegration per second.

High-touch Surfaces

Surfaces that are frequently touched by building users and occupants such as door knobs, hand rails and tables. See Table A1.

Infrared Radiation

Non-ionizing electromagnetic radiation having wavelengths between 700 and 1,000,000 nm.

Watershed

The region draining into a river, river system or other body of water.

Rod Cells

Photosensitive cells in the eye used to discern peripheral vision in low levels of illumination.

Syryl Phenol

A derived version of styrene, which is a colourless, oily liquid, used to manufacture polymers.

Thyroid Hormone Regulation

Regulation of thyroid hormones responsible for the physical and chemical processes that occur in cells, allow growth and maintain body functions.

Developmental Toxins

A subgroup of reproductive toxins that cause malformations of an embryo or fetus. Effects may occur from conception to sexual maturity and include spontaneous abortion, structural or functional defects, low birth weight or effects that may appear later in life.

Diabetes

A group of diseases that impact the metabolism due to insufficient insulin production (Type 1) and/or high insulin resistance (Type 2), and a leading cause of death. Results in poor blood sugar control, frequent urination, increased thirst, increased hunger and other symptoms.

Diabetic Ketoacidosis

A serious medical condition, not to be confused with "ketosis", in which a shortage of insulin forces triggering the production of ketones in extremely high quantities that can lead to toxic effects.

Diesel Particulate Matter (DPM)

Particulate component of diesel exhaust, which includes diesel soot and aerosols such as ash particulates, metallic abrasion particles, sulfates and silicates.

Virus

Any of various simple sub-microscopic parasites of plants, animals and bacteria that often cause disease and consist essentially of a core of genetic material surrounded by a protein shell.

Sound Wave

Sound waves are pressure variations in a medium (air, water, etc.). The pressure differences create vibrations and are ultimately interpreted as sounds/noises when they reach the ears.

Organochlorine

An organic compound that contains one or more chlorine atoms.

Mortality

The rate of death due to a disease or other cause.

Noise Cancellation

Noise cancellation is the methodology for cancelling sound through either active or passive means. Active noise cancelling uses signal processors to invert incoming signals and generate inverse waves for destructive interference. Passive noise cancelling utilizes insulation and sound-absorbing materials to reduce sound.

Ecotoxic

Substances that are poisonous to the ecosystem.

Efferent Pathway

Method of transmitting information from the central nervous system to muscles and organs.

Electromagnetic Radiation

Beam of energy composed at photons, which travel at the speed of light, 300,000 km/hr.

Vinyl Chloride Monomer (VCM)

A key compound componet used to create polyvinyl chloride.

Retina

Light-sensitive membrane found at the back end of the eyeball that receives the image produced by the lens.

Organic Compound

Member of a large class of gaseous, liquid or solid chemical compounds whose molecules contain carbon and hydrogen.

Morbidity

The rate of incidence of a disease.

Endothelial Injury Hypothesis

An alternative theory to the lipid hypothesis, positing that oxidized, relatively small, dense low-density-lipoproteins (LDL) are the primary cause of atherosclerotic plaque and CVD. This challenges the causal link between saturated fat intake and risk of heart disease.

Environmental Product Declaration (EPD)

Quantified environmental data for a product with pre-set categories of parameters based on the International Organization of Standards (ISO) 14040 series of standards, but not excluding additional environmental information.

Environmental Relative Moldiness Index (ERMI)

Rating of mold level based on sample of dust from within building. Takes degree of activity and toxicity of mold species.

Enzymes

Protein molecules made by the body that act as catalysts to modulate a vast array of biochemical reactions.

Ventilation Rate

Rate of exchange of outside air, as well as the circulation of air within the building.

Respiratory Failure

Inadequate gas exchange by the respiratory system, with the result that oxygen and/or carbon dioxide levels leaving the heart cannot be maintained within their normal ranges.

Organ of Corti

The organ of Corti contains the auditory hair cells that respond to the perilymph vibrations and transmit them into electrochemical impulses for the auditory nerve.

Monomer

A single molecule that may bind chemically with like others to create a ring or chain termed a polymer.

Reactive-oxygen Species (ROS)

A natural byproduct of oxygen metabolism, ROS are reactive oxygen intermediates vital to cell signaling and homeostasis. However, an over production of ROS, in times of environmental stress, can cause damage to cells structures.

Immunoassays

Test used to detect the presence or quantity of a substance based on its capacity to act as an antigen or antibody.

Erythema

Reddening of the skin caused by an excess in blood in the skin capillaries.

Influenza

An acute contagious viral infection characterized by inflammation of the respiratory tract and by fever, chills, muscular pain and prostration.

UV Index

Measure of ultraviolet radiation, usually ranging from 1 to 12 during the day on earth. Each unit equals 25 mW/m², weighted to the human erythema response.

Respiration

The act of breathing or the heating of incoming air to the core body temperature (CBT) then breathing out.

Substitution Combustibles

Alternative fuels or raw materials used in combustion processes.

Neurocognitive Diseases

Diseases of the brain and nervous system.

Fenestration

An opening in a surface (as a wall or membrane).

Fetotoxicity

Resulting in toxicity of the fetus.

Fibrosis

A condition marked by an increase of fibrous tissue between tissue or part of an organ, whether in a reparative or reactive process.

Inflammatory Bowel Disease (IBD)

A group of autoimmune diseases of the colon and small intestine, including chron's disease and ulcerative colitis.

Immuno-compromised

An inability to develop a normal immune response, usually as a result of disease, malnutrition or medical therapy that affects the immune system.

Reproductive Toxins

A poison that targets the reproductive system.

Nuclide

A specific designation of atom characterized by giving the number of protons and neutrons in the nucleus.

Rancidification

The process by which fats, oils and other lipids are decomposed, often resulting in undesirable odors and flavors, reducing nutritional value and introducing harmful oxidative compounds.

Food and Drug Administration (FDA)

The Food and Drug Administration (FDA) is an agency within the U.S. Department of Health and Human Services. The core functions of the agency are: Medical Products and Tobacco, Foods and Veterinary Medicine, Global Regulatory Operations and Policy and Operations.

Food Intolerances

Food sensitivity usually caused by difficulty digesting a particular food that does not involve an immune system response or the release of histamine.

Highly-processed Oils

Oils that are highly processed to remove impurities and therefore to withstand cooking heat. This usually leaves the oils prone to oxidation.

Metabolic

Any biochemical process that occurs within an organism that is necessary to sustain life.

Ultraviolet Germicidal Irradiation (UVGI)

A sterilization method that uses ultraviolet (UV) light to break down microorganisms by destroying their DNA. Often used in a variety of applications, such as food, air and water purification.

Regularly Occupied Space

An areas where workers or other building occupants perform focused activities inside a building for an average of one hour a day or more.

Heat Recovery Ventilation (HRV)

Ventilation system that employs an air to air heat exchanger for the transfer of moisture and heat from outbound air to inbound circulated air.

Trimester

One third (or approximately 13 weeks) of pregnancy.

Full Time Employee

A full time employee is one who works at least the minimum amount of hours as definied by his or her employer. This is generally defined as 8 hours a day, 5 days a week.

Fungi

Any of a group of unicellular, multicellular or syncytial spore-producing organisms feeding on organic materials.

Pulmonary Edema

Abnormal accumulation of fluid in the lungs

Furans

One of a group of colorless, volatile, heterocyclic organic compounds

Ultrasound

Sound waves with frequencies greater than 20 kHz. Too high for the human ear to hear.

Reference Dose (RfD)

Daily ingestion level of at substance believed to have no harmful effect to most people. Typically 100 to 1000 times less the No Observed Adverse Effects Level, and sometimes 10 times larger than the Population Adjusted Dose.

NSF (formerly National Sanitation Foundation)

A standard by which water filters are judged.

Hyperpallatable

Food that is designed, engineered or marketed to be as desirable as possible. Often characterized by the presence of excessive salt, sweeteners and oils, these foods can overcome feelings of satiety to induce overeating..

Genotoxic

A chemical or other agent that damages genetic material or reproduction, resulting in mutations or cancer.

Giardia

Protozoa that can live in the small intestine of humans and lead to severe digestive problems.

Glazing

Glasswork, which must be carefully designed in order to avoid excessive glare and heat gain.

Glioma

Cancer which arises in the glial cells of the brain and spinal column.

Ulcerative Colitis

An inflammatory bowel disease (IBD) that causes long-lasting inflammation in the large intestine and rectum characterized by recurrent episodes of abdominal pain, fever and diarrhea.

N-nitrosodimethylamine (NDMA)

Most commonly detected nitrosamine in water supplies. Likely carcinogenic and formed as a result of reactions with chloramine.

Non-REM Sleep

Non-rapid eye movement, or non-REM is, collectively, sleep stages 1–3. There are distinct electroencephalographic and other characteristics seen in each stage. Unlike REM sleep, there is usually little or no eye movement during this stage.

Micrometer (µm)

International system unit of length equal to one-millionth of a meter.

Glycolysis

Process of metabolism which occurs during strenuous exercise in which cells produce ATP anaerobically and generate lactic acid as a byproduct.

Intermittent Fasting

Any eating pattern in which the timing of calorie-consumption is restricted on a daily or weekly basis. A common intermittent fasting pattern is characterized by an 8-hour eating window and a 16-hour fasting period.

Growth Hormone

A hormone that stimulates growth, cell reproduction and regeneration. It has an anabolic effect on the body, playing a critical role in childhood development and organ and muscle growth. It is boosted in the body during fasting, restful sleep and exercise.

Gypsum

Gypsum is a soft sulfate mineral composed of calcium disulfate and commonly used in drywall and plasters.

Tympanic Membrane

Membrane in the ear canal that separates the external ear from the middle ear; more commonly known as eardrum.

Toxilogical Testing

Conducted to determine safety by ascertaining how damaging a given chemical may be to living or non-living organisms.