Appendix A: Glossary
| Ventilation Rate |
Rate of exchange of outside air, as well as the circulation of air within the building. |
| Sensory Neurons |
Nerve cells which relay messages from sensory organs to the CNS. |
| Healthy Building Network |
An organization that publishes and researches information on the sustainability of building materials and advocates environmentally friendly building materials and building policies. |
| Heart Disease |
A class of disease that affects the heart, arteries, capillaries or veins. |
| Heat Recovery Ventilation (HRV) |
Ventilation system that employs an air to air heat exchanger for the transfer of moisture and heat from outbound air to inbound circulated air. |
| Heating, Ventilating, and Air Conditioning System (HVAC) |
Equipment, distribution systems and terminals that provide the processes of heating, ventilating or air conditioning. |
| Hemoglobin | |
| Organ of Corti |
The organ of Corti contains the auditory hair cells that respond to the perilymph vibrations and transmit them into electrochemical impulses for the auditory nerve. |
| UV Index | |
| Sensitization |
Exposure to an allergen that results in the development of hypersensitivity. |
| Highly-processed Oils |
Oils that are highly processed to remove impurities and therefore to withstand cooking heat. This usually leaves the oils prone to oxidation. |
| High-touch Surfaces |
Surfaces that are frequently touched by building users and occupants such as door knobs, hand rails and tables. See Table A1. |
| Homeostasis |
A state of having regulated responses to environmental conditions to retain stability. |
| Hormone Disruptors |
A chemical that interferes with the signalling of the endocrine system in mammals and that can lead to developmental disorders, birth defects and cancer. |
| Reference Dose (RfD) |
Daily ingestion level of at substance believed to have no harmful effect to most people. Typically 100 to 1000 times less the No Observed Adverse Effects Level, and sometimes 10 times larger than the Population Adjusted Dose. |
| Humidifier Fever | |
| Uptake |
Act of absorbing, especially into a living organism. |
| No Observed Adverse Effect Level (NOAEL) |
Daily ingestion level of at substance shown to have no harmful effect on laboratory test animals. Typically 100 to 1000 times larger than the Reference Dose. |
| Hydrogen Sulfide |
A colorless, flammable, water-soluble, poisonous gas, having the odor of rotten eggs and used in the manufacture of chemicals, in metallurgy and as a reagent. |
| Toluene Diisocyanate |
Clear, colorless to pale-yellow liquid with a pungent odor. Used primarily to manufacture flexible polyurethane foams for use in furniture, bedding and automotive and airline seats. |
| Hygrothermal |
A term used to connect heat and moisture flows and their combined effect on building envelope (enclosure) performance. |
| Hyperpallatable |
Food that is designed, engineered or marketed to be as desirable as possible. Often characterized by the presence of excessive salt, sweeteners and oils, these foods can overcome feelings of satiety to induce overeating.. |
| Hypersensitivity |
Oversensitivity or an exaggerated immune response to what is perceived as a foreign substance. |
| Hypersensitivity Pneumonitis |
An inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts. Symptoms usually include fever, chills, fatigue, breathlessness, cough and chest tightness. |
| Universal Design (UD) |
Designing objects and spaces with aesthetically pleasing while maximizing accessibility, usability and operability regardless of the user's age, ability and other factors. |
| Teratogenic |
Disrupting the development of the embryo or fetus. |
| Hypothalamic-pituitary-gonadal (HPG) axis |
Part of the hypothalamus which regulates sex hormone release. |
| Hypothalamus |
Part of the brain that links the endocrine system with the nervous system through the pituitary gland. |
| Hypothyroidism |
A condition in which the thyroid gland does not produce enough of certain hormones, which over time can lead to several health problems including overweight and obesity, joint pain and heart disease. |
| Hypoxia | |
| Igneous Rock |
Rock formed by the solidification of molten magma. |
| Motor Neurons |
Nerve cells which transmit signals from the CNS to muscles and glands. |
| Ultraviolet Germicidal Irradiation (UVGI) |
A sterilization method that uses ultraviolet (UV) light to break down microorganisms by destroying their DNA. Often used in a variety of applications, such as food, air and water purification. |
| Schizophrenia |
A psychotic disorder characterized by loss of contact with the environment, by noticeable deterioration in the level of functioning in everyday life and by disintegration of personality expressed as disorder of feeling, thought, perception and behavior. |
| Immune System |
The integrated body system of organs, tissues, cells and cell products such as antibodies that differentiates self from non-self and neutralizes potentially harmful organisms or substances. |
| Immunoassays | |
| Immuno-compromised |
An inability to develop a normal immune response, usually as a result of disease, malnutrition or medical therapy that affects the immune system. |
| Immunosuppressive |
Any compound or substance that may impair proper immune functioning. |
| Nanocrystalline Silica (sio2) |
A form of the chemical element silicon that has introduced nanoporous holes in its microstructure. |
| Incus | |
| Ultrasound |
Sound waves with frequencies greater than 20 kHz. Too high for the human ear to hear. |
| Scavenging Free Radicals |
A chemical compound or substance that inhibits oxidation by neutralizing the oxidant effect of free radicals |
| Inflammatory Bowel Disease (IBD) |
A group of autoimmune diseases of the colon and small intestine, including chron's disease and ulcerative colitis. |
| Influenza |
An acute contagious viral infection characterized by inflammation of the respiratory tract and by fever, chills, muscular pain and prostration. |
| Infrared Radiation |
Non-ionizing electromagnetic radiation having wavelengths between 700 and 1,000,000 nm. |
| Infrasound |
Sound waves with frequencies less than 20 Hz. Too low for the human ear to hear. |
| Toxilogical Testing |
Conducted to determine safety by ascertaining how damaging a given chemical may be to living or non-living organisms. |
| Insecticides |
Chemicals applied to crops or structures to reduce the harmful effects of insect pests. |
| Ulcerative Colitis |
An inflammatory bowel disease (IBD) that causes long-lasting inflammation in the large intestine and rectum characterized by recurrent episodes of abdominal pain, fever and diarrhea. |
| Sarcopenia |
Age related loss of skeletal muscle mass, including quality and strength. |
| Interesterified Fat |
A type of oil in which fatty acids held in triglycerides have been reconfigured. These fats were designed to replace trans-fats in commercial baked goods and processed foods. There is little known about their health effects. |
| Intermittent Fasting |
Any eating pattern in which the timing of calorie-consumption is restricted on a daily or weekly basis. A common intermittent fasting pattern is characterized by an 8-hour eating window and a 16-hour fasting period. |
| Intervertabal Disc |
Intervertebral discs (IVD) are the cartilaginous joints that lie between adjacent vertebra in the spine. Each disc allows slight movement of the vertebrae and acts as a ligament to hold the vertebrae together. |
| Intracellular |
The space inside of a cell. |
| Intrinsically Photoreceptive Retinal Ganglion Cells (ipRGCs) |
Relay environmental light levels to the suprachiasmatic nucleus through the retinohypothalamic tract. Most sensitive to blue light. |
| Ionization |
The process by which an atom or a molecule looses or gains an electron thereby acquiring a negative or positive charge. |
| Nuclide |
A specific designation of atom characterized by giving the number of protons and neutrons in the nucleus. |
| Safe Drinking Water Act of 1974 |
Passed by congress in 1974, authorizing the EPA to set national limits on contaminant levels in drinking water making it safe for human consumption. Under this program, EPA regulates public water systems that provide "piped water for human consumption" and serve at least 25 individuals or has 15 service connections. |
| Ketones |
Nourishing, neuroprotective and immune-supporting compounds that are converted from dietary medium-chained fatty acids in the liver. Ketone-producing diets increase HDL, improve weight loss and kill or inhibit the growth of parasites, viruses and fungi. Ketogenic diets can protect and heal neurons, improving spinal injury recovery time, reducing the severity of and in some cases reversing epilepsy, alzheimers, MS and parkinson's disease, autism and schizophrenia. |
| Krebs Cycle |
Process of metabolism in which cells produce ATP aerobically within the mitochondria and is the primary energy process of cells. |
| Lactic Acid |
Eventual product of glucose in cells during metabolism which, when its production exceeds a cell's ability to remove it, contributes to the "burning" sensation in exercise. |
| Parasite |
An organism that lives in or on another organism (its host) and benefits by deriving nutrients at the host's expense. |
| Legionella |
Bacterium that thrives in moist conditions found in central heating and air conditioning systems that can cause Legionnaires' disease. |
| Legionnaires' Disease |
A type of pneumonia caused by bacteria. It is initially characterized by symptoms resembling the flu followed by high fever, cough, diarrhea and mental confusion, and may be fatal especially in elderly and individuals with weakened immune systems. |
| Type II Diabetes |
The most common form of diabetes, usually appearing in middle aged adults and often associated with obesity and may be controlled with diet and exercise. In type II diabetes the cells are not responding properly to the insulin, and/or there is not enough insulin being produced. |
| Rod Cells |
Photosensitive cells in the eye used to discern peripheral vision in low levels of illumination. |
| Neurodegeneration |
An umbrella term for the progressive loss of structure or function of the brain. |
| Lipid Hypothesis |
The theory positing a causal link between higher dietary saturated fat and cholesterol intake with plasma lipoprotein composition and heart disease. |
| Lipophilic |
The affinity or dissolvability of a compound in fat or oil. |
| Liver | |
| Living Building Challenge |
The Living Building Challenge is a certification program for sustainability of the built environment. |
| Longitudinal Wave |
Type of one-dimensional wave made of compressions and rarefactions when traveling through a medium. Characteristics of longitidunal waves are that the distance between the peaks increases and decreases with oscillations. |
| Type I Diabetes |
Also called juvenile diabetes, type I diabetes usually begins early in life. Affected individuals are unable to produce insulin and must take insulin injections. |
| The Centers for Disease Control and Prevention (CDC) |
The Centers for Disease Control and Prevention (CDC) is America's health protection agency against key health threats. |
| Lowest Observed Adverse Effect Level (LOAEL) |
Smallest level of daily ingestion of at substance shown to have some harmful effect on laboratory test animals. Always larger than the No Observed Adverse Effect Level. |
| The Toxic Substances Control Act (TSCA) |
A law passed in the 1970s that regulates the introduction of new or already existing chemicals. |
| National Pollutant Discharge Elimination System (NPDES) |
Permit program established by the federal government in 1972 to control point-source discharges of wastewater to lakes, streams, wetlands and other surface waters. |
| Tracheo-bronchial Region |
Area of the windpipe and the two major air passages of the lungs that diverge from the windpipe. |
| Myopia |
Nearsightedness or shortsightedness, caused by light being focused in front of the retina rather than on it. |
| Mortality |
The rate of death due to a disease or other cause. |
| Respiratory Failure |
Inadequate gas exchange by the respiratory system, with the result that oxygen and/or carbon dioxide levels leaving the heart cannot be maintained within their normal ranges. |
| Retinal Hemorrhage |
Abnormal bleeding of the blood vessels in the retina, the membrane in the back of the eye. |
| Malabsorption |
Defective or insufficient absorption of nutrients from the small intestine. |
| Malleus |
Mallet shaped bone in the middle ear located between the incus and the tympanic membrane (eardrum). |
| Malnutrition |
A condition that results from insufficient nutrient intake, excess nutrient intake or nutrient intake in the wrong proportions. |
| Paraformaldehyde |
A solid thermoplastic form of liquid formaldehyde. |
| Myocardial Infarction |
An acute episode of heart disease marked by the damage of heart muscle due to insufficient blood supply to the heart muscle, also called a heart attack. |
| Morbidity |
The rate of incidence of a disease. |
| Tuberculosis | |
| N-nitrosodimethylamine (NDMA) |
Most commonly detected nitrosamine in water supplies. Likely carcinogenic and formed as a result of reactions with chloramine. |
| Photopic Sensitivity |
The eye's response to brightness using a combination of the M and L cones. Most sensitive to light at 555 nm. |
| Mesothelioma |
A disease that causes the formation of malignant cancer cells within the lining of the chest, abdomen or heart. |
| Metabolic |
Any biochemical process that occurs within an organism that is necessary to sustain life. |
| Metabolic Dysregulation |
The suite of conditions associated with metabolic syndrome. |
| Mycotoxins |
Toxins produced by some species of mold, the toxins are very dangerous to humans and animals. |
| Metabolic Syndrome | |
| Tympanic Membrane |
Membrane in the ear canal that separates the external ear from the middle ear; more commonly known as eardrum. |
| Retina |
Light-sensitive membrane found at the back end of the eyeball that receives the image produced by the lens. |
| Methane |
The simplest organic compound - made up of four carbon-hydrogen bonds. |
| Persistent Organic Pollutants (POPS) |
Organic compounds that are resistant to environmental degradation through chemical, biological and photolytic processes. |
