This is a legacy version of the WELL Building Standard. Please check the latest version here.

Appendix A: Glossary

General Terms

Ventilation Rate

Rate of exchange of outside air, as well as the circulation of air within the building.

Sensory Neurons

Nerve cells which relay messages from sensory organs to the CNS.

Healthy Building Network

An organization that publishes and researches information on the sustainability of building materials and advocates environmentally friendly building materials and building policies.

Heart Disease

A class of disease that affects the heart, arteries, capillaries or veins.

Heat Recovery Ventilation (HRV)

Ventilation system that employs an air to air heat exchanger for the transfer of moisture and heat from outbound air to inbound circulated air.

Heating, Ventilating, and Air Conditioning System (HVAC)

Equipment, distribution systems and terminals that provide the processes of heating, ventilating or air conditioning.

Hemoglobin

Iron-containing protein which red blood cells their characteristic color and functions primarily in the transport of oxygen from the lungs to the tissues of the body.

Organ of Corti

The organ of Corti contains the auditory hair cells that respond to the perilymph vibrations and transmit them into electrochemical impulses for the auditory nerve.

UV Index

Measure of ultraviolet radiation, usually ranging from 1 to 12 during the day on earth. Each unit equals 25 mW/m², weighted to the human erythema response.

Sensitization

Exposure to an allergen that results in the development of hypersensitivity.

Highly-processed Oils

Oils that are highly processed to remove impurities and therefore to withstand cooking heat. This usually leaves the oils prone to oxidation.

High-touch Surfaces

Surfaces that are frequently touched by building users and occupants such as door knobs, hand rails and tables. See Table A1.

Homeostasis

A state of having regulated responses to environmental conditions to retain stability.

Hormone Disruptors

A chemical that interferes with the signalling of the endocrine system in mammals and that can lead to developmental disorders, birth defects and cancer.

Reference Dose (RfD)

Daily ingestion level of at substance believed to have no harmful effect to most people. Typically 100 to 1000 times less the No Observed Adverse Effects Level, and sometimes 10 times larger than the Population Adjusted Dose.

Humidifier Fever

Flu-like illness marked by fever, headache, chills and malaise but without prominent pulmonary symptoms. It is a disease of uncertain origin, with onset occurring a few hours after exposure usually to amoebae, bacteria and fungi found in humidifier reservoirs, air conditioners and aquaria.

Uptake

Act of absorbing, especially into a living organism.

No Observed Adverse Effect Level (NOAEL)

Daily ingestion level of at substance shown to have no harmful effect on laboratory test animals. Typically 100 to 1000 times larger than the Reference Dose.

Hydrogen Sulfide

A colorless, flammable, water-soluble, poisonous gas, having the odor of rotten eggs and used in the manufacture of chemicals, in metallurgy and as a reagent.

Toluene Diisocyanate

Clear, colorless to pale-yellow liquid with a pungent odor. Used primarily to manufacture flexible polyurethane foams for use in furniture, bedding and automotive and airline seats.

Hygrothermal

A term used to connect heat and moisture flows and their combined effect on building envelope (enclosure) performance.

Hyperpallatable

Food that is designed, engineered or marketed to be as desirable as possible. Often characterized by the presence of excessive salt, sweeteners and oils, these foods can overcome feelings of satiety to induce overeating..

Hypersensitivity

Oversensitivity or an exaggerated immune response to what is perceived as a foreign substance.

Hypersensitivity Pneumonitis

An inflammation of the alveoli within the lung caused by hypersensitivity to inhaled organic dusts. Symptoms usually include fever, chills, fatigue, breathlessness, cough and chest tightness.

Universal Design (UD)

Designing objects and spaces with aesthetically pleasing while maximizing accessibility, usability and operability regardless of the user's age, ability and other factors.

Teratogenic

Disrupting the development of the embryo or fetus.

Hypothalamic-pituitary-gonadal (HPG) axis

Part of the hypothalamus which regulates sex hormone release.

Hypothalamus

Part of the brain that links the endocrine system with the nervous system through the pituitary gland.

Hypothyroidism

A condition in which the thyroid gland does not produce enough of certain hormones, which over time can lead to several health problems including overweight and obesity, joint pain and heart disease.

Hypoxia

Hypoxia is an abnormal condition of the body in which oxygen intake or use is inadequate causing a deficiency in the amount of oxygen reaching body tissues.

Igneous Rock

Rock formed by the solidification of molten magma.

Motor Neurons

Nerve cells which transmit signals from the CNS to muscles and glands.

Ultraviolet Germicidal Irradiation (UVGI)

A sterilization method that uses ultraviolet (UV) light to break down microorganisms by destroying their DNA. Often used in a variety of applications, such as food, air and water purification.

Schizophrenia

A psychotic disorder characterized by loss of contact with the environment, by noticeable deterioration in the level of functioning in everyday life and by disintegration of personality expressed as disorder of feeling, thought, perception and behavior.

Immune System

The integrated body system of organs, tissues, cells and cell products such as antibodies that differentiates self from non-self and neutralizes potentially harmful organisms or substances.

Immunoassays

Test used to detect the presence or quantity of a substance based on its capacity to act as an antigen or antibody.

Immuno-compromised

An inability to develop a normal immune response, usually as a result of disease, malnutrition or medical therapy that affects the immune system.

Immunosuppressive

Any compound or substance that may impair proper immune functioning.

Nanocrystalline Silica (sio2)

A form of the chemical element silicon that has introduced nanoporous holes in its microstructure.

Incus

Anvil shaped bone in the middle ear located between the malleus and stapes. The incus transmits vibrations from the malleus to the stapes.

Ultrasound

Sound waves with frequencies greater than 20 kHz. Too high for the human ear to hear.

Scavenging Free Radicals

A chemical compound or substance that inhibits oxidation by neutralizing the oxidant effect of free radicals

Inflammatory Bowel Disease (IBD)

A group of autoimmune diseases of the colon and small intestine, including chron's disease and ulcerative colitis.

Influenza

An acute contagious viral infection characterized by inflammation of the respiratory tract and by fever, chills, muscular pain and prostration.

Infrared Radiation

Non-ionizing electromagnetic radiation having wavelengths between 700 and 1,000,000 nm.

Infrasound

Sound waves with frequencies less than 20 Hz. Too low for the human ear to hear.

Toxilogical Testing

Conducted to determine safety by ascertaining how damaging a given chemical may be to living or non-living organisms.

Insecticides

Chemicals applied to crops or structures to reduce the harmful effects of insect pests.

Ulcerative Colitis

An inflammatory bowel disease (IBD) that causes long-lasting inflammation in the large intestine and rectum characterized by recurrent episodes of abdominal pain, fever and diarrhea.

Sarcopenia

Age related loss of skeletal muscle mass, including quality and strength.

Interesterified Fat

A type of oil in which fatty acids held in triglycerides have been reconfigured. These fats were designed to replace trans-fats in commercial baked goods and processed foods. There is little known about their health effects.

Intermittent Fasting

Any eating pattern in which the timing of calorie-consumption is restricted on a daily or weekly basis. A common intermittent fasting pattern is characterized by an 8-hour eating window and a 16-hour fasting period.

Intervertabal Disc

Intervertebral discs (IVD) are the cartilaginous joints that lie between adjacent vertebra in the spine. Each disc allows slight movement of the vertebrae and acts as a ligament to hold the vertebrae together.

Intracellular

The space inside of a cell.

Intrinsically Photoreceptive Retinal Ganglion Cells (ipRGCs)

Relay environmental light levels to the suprachiasmatic nucleus through the retinohypothalamic tract. Most sensitive to blue light.

Ionization

The process by which an atom or a molecule looses or gains an electron thereby acquiring a negative or positive charge.

Nuclide

A specific designation of atom characterized by giving the number of protons and neutrons in the nucleus.

Safe Drinking Water Act of 1974

Passed by congress in 1974, authorizing the EPA to set national limits on contaminant levels in drinking water making it safe for human consumption. Under this program, EPA regulates public water systems that provide "piped water for human consumption" and serve at least 25 individuals or has 15 service connections.

Ketones

Nourishing, neuroprotective and immune-supporting compounds that are converted from dietary medium-chained fatty acids in the liver. Ketone-producing diets increase HDL, improve weight loss and kill or inhibit the growth of parasites, viruses and fungi. Ketogenic diets can protect and heal neurons, improving spinal injury recovery time, reducing the severity of and in some cases reversing epilepsy, alzheimers, MS and parkinson's disease, autism and schizophrenia.

Krebs Cycle

Process of metabolism in which cells produce ATP aerobically within the mitochondria and is the primary energy process of cells.

Lactic Acid

Eventual product of glucose in cells during metabolism which, when its production exceeds a cell's ability to remove it, contributes to the "burning" sensation in exercise.

Parasite

An organism that lives in or on another organism (its host) and benefits by deriving nutrients at the host's expense.

Legionella

Bacterium that thrives in moist conditions found in central heating and air conditioning systems that can cause Legionnaires' disease.

Legionnaires' Disease

A type of pneumonia caused by bacteria. It is initially characterized by symptoms resembling the flu followed by high fever, cough, diarrhea and mental confusion, and may be fatal especially in elderly and individuals with weakened immune systems.

Type II Diabetes

The most common form of diabetes, usually appearing in middle aged adults and often associated with obesity and may be controlled with diet and exercise. In type II diabetes the cells are not responding properly to the insulin, and/or there is not enough insulin being produced.

Rod Cells

Photosensitive cells in the eye used to discern peripheral vision in low levels of illumination.

Neurodegeneration

An umbrella term for the progressive loss of structure or function of the brain.

Lipid Hypothesis

The theory positing a causal link between higher dietary saturated fat and cholesterol intake with plasma lipoprotein composition and heart disease.

Lipophilic

The affinity or dissolvability of a compound in fat or oil.

Liver

An organ that plays a vital role in a range of important metabolic processes including detoxification, protein synthesis and glycogen storage.

Living Building Challenge

The Living Building Challenge is a certification program for sustainability of the built environment.

Longitudinal Wave

Type of one-dimensional wave made of compressions and rarefactions when traveling through a medium. Characteristics of longitidunal waves are that the distance between the peaks increases and decreases with oscillations.

Type I Diabetes

Also called juvenile diabetes, type I diabetes usually begins early in life. Affected individuals are unable to produce insulin and must take insulin injections.

The Centers for Disease Control and Prevention (CDC)

The Centers for Disease Control and Prevention (CDC) is America's health protection agency against key health threats.

Lowest Observed Adverse Effect Level (LOAEL)

Smallest level of daily ingestion of at substance shown to have some harmful effect on laboratory test animals. Always larger than the No Observed Adverse Effect Level.

The Toxic Substances Control Act (TSCA)

A law passed in the 1970s that regulates the introduction of new or already existing chemicals.

National Pollutant Discharge Elimination System (NPDES)

Permit program established by the federal government in 1972 to control point-source discharges of wastewater to lakes, streams, wetlands and other surface waters.

Tracheo-bronchial Region

Area of the windpipe and the two major air passages of the lungs that diverge from the windpipe.

Myopia

Nearsightedness or shortsightedness, caused by light being focused in front of the retina rather than on it.

Mortality

The rate of death due to a disease or other cause.

Respiratory Failure

Inadequate gas exchange by the respiratory system, with the result that oxygen and/or carbon dioxide levels leaving the heart cannot be maintained within their normal ranges.

Retinal Hemorrhage

Abnormal bleeding of the blood vessels in the retina, the membrane in the back of the eye.

Malabsorption

Defective or insufficient absorption of nutrients from the small intestine.

Malleus

Mallet shaped bone in the middle ear located between the incus and the tympanic membrane (eardrum).

Malnutrition

A condition that results from insufficient nutrient intake, excess nutrient intake or nutrient intake in the wrong proportions.

Paraformaldehyde

A solid thermoplastic form of liquid formaldehyde.

Myocardial Infarction

An acute episode of heart disease marked by the damage of heart muscle due to insufficient blood supply to the heart muscle, also called a heart attack.

Morbidity

The rate of incidence of a disease.

Tuberculosis

Infectious disease usually spread by inhalation of the airborne bacteria. Chiefly affects the lungs but may spread to other areas. Characterized by fever, cough, difficulty breathing and fibrosis.

N-nitrosodimethylamine (NDMA)

Most commonly detected nitrosamine in water supplies. Likely carcinogenic and formed as a result of reactions with chloramine.

Photopic Sensitivity

The eye's response to brightness using a combination of the M and L cones. Most sensitive to light at 555 nm.

Mesothelioma

A disease that causes the formation of malignant cancer cells within the lining of the chest, abdomen or heart.

Metabolic

Any biochemical process that occurs within an organism that is necessary to sustain life.

Metabolic Dysregulation

The suite of conditions associated with metabolic syndrome.

Mycotoxins

Toxins produced by some species of mold, the toxins are very dangerous to humans and animals.

Metabolic Syndrome

A cluster of medical conditions or risk factors that increase the chances of developing cardiovascular disease, diabetes fatty liver disease and several cancers.

Tympanic Membrane

Membrane in the ear canal that separates the external ear from the middle ear; more commonly known as eardrum.

Retina

Light-sensitive membrane found at the back end of the eyeball that receives the image produced by the lens.

Methane

The simplest organic compound - made up of four carbon-hydrogen bonds.

Persistent Organic Pollutants (POPS)

Organic compounds that are resistant to environmental degradation through chemical, biological and photolytic processes.