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Appendix A: Glossary

General Terms

Lactic Acid

Eventual product of glucose in cells during metabolism which, when its production exceeds a cell's ability to remove it, contributes to the "burning" sensation in exercise.

Legionella

Bacterium that thrives in moist conditions found in central heating and air conditioning systems that can cause Legionnaires' disease.

Legionnaires' Disease

A type of pneumonia caused by bacteria. It is initially characterized by symptoms resembling the flu followed by high fever, cough, diarrhea and mental confusion, and may be fatal especially in elderly and individuals with weakened immune systems.

Leukemia

Blood cancer characterized by an abnormal increase in the number of white blood cells in the tissues of the body.

Life Cycle Analysis

A technique to inspect environmental impacts associated with all the stages of a product's life from beginning to end.

Lipid Hypothesis

The theory positing a causal link between higher dietary saturated fat and cholesterol intake with plasma lipoprotein composition and heart disease.

Lipophilic

The affinity or dissolvability of a compound in fat or oil.

Liver

An organ that plays a vital role in a range of important metabolic processes including detoxification, protein synthesis and glycogen storage.

Living Building Challenge

The Living Building Challenge is a certification program for sustainability of the built environment.

Longitudinal Wave

Type of one-dimensional wave made of compressions and rarefactions when traveling through a medium. Characteristics of longitidunal waves are that the distance between the peaks increases and decreases with oscillations.

Low Density Lipoproteins (LDL)

One of the major groups of lipoprotiens produced in the liver that enable the movement of fat and cholesterol through the blood.

Low FODMAP Diet

An acronym standing for: Fermentable Oligo-, Di- and Mono-saccharides and Polyols. The diet is based on the theory that foods containing the aforementioned forms of carbohydrates exacerbate symptoms of digestive disorders, such as irritable bowel syndrome (IBS) and inflammatory bowel disease (IBD).

Lowest Observed Adverse Effect Level (LOAEL)

Smallest level of daily ingestion of at substance shown to have some harmful effect on laboratory test animals. Always larger than the No Observed Adverse Effect Level.

Lymphohematopoietic

Relating to or involved in the production of lymphocytes and cells of blood, bone marrow, spleen, lymph nodes and thymus.

Malabsorption

Defective or insufficient absorption of nutrients from the small intestine.

Malleus

Mallet shaped bone in the middle ear located between the incus and the tympanic membrane (eardrum).

Malnutrition

A condition that results from insufficient nutrient intake, excess nutrient intake or nutrient intake in the wrong proportions.

Mesothelioma

A disease that causes the formation of malignant cancer cells within the lining of the chest, abdomen or heart.

Metabolic

Any biochemical process that occurs within an organism that is necessary to sustain life.

Metabolic Dysregulation

The suite of conditions associated with metabolic syndrome.

Metabolic Syndrome

A cluster of medical conditions or risk factors that increase the chances of developing cardiovascular disease, diabetes fatty liver disease and several cancers.

Metamers

Different spectral distributions of light which produce the same response on the cones and are therefore visually identical.

Metamorphic Rock

A rock formed from preexisting solid rocks through the influence of heat, pressure or other agent.

Methane

The simplest organic compound - made up of four carbon-hydrogen bonds.

Micrometer (µm)

International system unit of length equal to one-millionth of a meter.

Minimum Erythemal Dose (MED)

Smallest dose of ultraviolet radiation which causes a barely perceptible reddening of the skin. Depended on the skin color of an individual.

Mitochondria

A cellular organelle that has the ability to convert nutrients into ATP, an energy-rich molecule used in virtually every metabolic process.

Monomer

A single molecule that may bind chemically with like others to create a ring or chain termed a polymer.

Morbidity

The rate of incidence of a disease.

Mortality

The rate of death due to a disease or other cause.

Motor Neurons

Nerve cells which transmit signals from the CNS to muscles and glands.

Mucosa

The mucus membrane that lines the gastrointestinal tract and other body cavities. Plays an important role in protecting against pathogens.

Mumps

Viral disease causing painful swelling of the glands in the mouth that produces saliva. The disease is generally self-limited, running its course before receding, with no specific treatment apart from controlling the symptoms with pain medication.

Mutagen

A physical or chemical agent that changes the genetic material of an organism and increases the frequency of mutations above what would naturally occur.

Mycotoxins

Toxins produced by some species of mold, the toxins are very dangerous to humans and animals.

Myocardial Infarction

An acute episode of heart disease marked by the damage of heart muscle due to insufficient blood supply to the heart muscle, also called a heart attack.

Myopia

Nearsightedness or shortsightedness, caused by light being focused in front of the retina rather than on it.

Nanocrystalline Silica (sio2)

A form of the chemical element silicon that has introduced nanoporous holes in its microstructure.

Nanomaterials

A material having particles or constituents of nanoscale dimensions.

Nanoparticles

Particles between 1 and 100 nanometers in size.

Nap Pod

A personal dedicated resting space optimized to offer a short but regenerative sleep.

Nasal-pharyngeal Region

Part of the respiratory system, between the nose and the throat, at the level of the fleshy, flexible part at the back of the roof of the mouth.

National Ambient Air Quality Standards (NAAQS)

The National Ambient Air Quality Standards (NAAQS) are concentration limits set by the EPA for six pollutants known as criteria air pollutants; The NAAQS's primary standards set limits that protect public health, including sensitive populations, while the secondary standard limits are set to protect public welfare, such as visibility impairment and damage crops.

National Pollutant Discharge Elimination System (NPDES)

Permit program established by the federal government in 1972 to control point-source discharges of wastewater to lakes, streams, wetlands and other surface waters.

National Secondary Drinking Water Regulations (NSDWR)

Non-enforced limits of select drinking water contaminants. Mainly target minerals which affect water taste and enter the water through natural deposits.

National Toxicology Program (NTP)

An agency program run by the United States Department of Health and Human Services to maintain and report on toxicology.

National Ventilation Procedure

ANSI/ASHRAE Standards 62.1 is the recognized standard for ventilation system design and acceptable procedure with regards to establishing an effective ventilation system.

Naturally Occurring Radioactive Materials (NORM)

All radioactive elements found in the environment naturally.

Neural Damage

Injury to the brain that is caused by various conditions and may be associated with a behavioral or functional abnormality.

Neurocognitive Diseases

Diseases of the brain and nervous system.

Neurodegeneration

An umbrella term for the progressive loss of structure or function of the brain.

Neurons

A specialized cell of the nervous system that transmits electrochemical signals.

Neurosecretory Cells

Neurons in the hypothalamus which release hormones into the blood.

Neurotoxins

A poison that targets the nervous system, disrupting proper neuron-signalling.

Neurotransmitter

Chemicals that transmit signals from a neuron to a target cell across a synapse. These are an essential component of a functioning nervous system.

N-nitrosodimethylamine (NDMA)

Most commonly detected nitrosamine in water supplies. Likely carcinogenic and formed as a result of reactions with chloramine.

No Observed Adverse Effect Level (NOAEL)

Daily ingestion level of at substance shown to have no harmful effect on laboratory test animals. Typically 100 to 1000 times larger than the Reference Dose.

Noise Cancellation

Noise cancellation is the methodology for cancelling sound through either active or passive means. Active noise cancelling uses signal processors to invert incoming signals and generate inverse waves for destructive interference. Passive noise cancelling utilizes insulation and sound-absorbing materials to reduce sound.

Noise Induced Hearing Loss (NIHL)

Excessive exposure to loud sounds can result in NIHL through wearing down of the auditory hair cells. The cells wear down because of the oxidating byproducts created through the electrochemicals reactions between the perilymph fluid and the auditory hair cells.

Noncompliant

In terms of air pollution, regions are noncompliant if they fail to achieve standards set by NAAQS.

Non-REM Sleep

Non-rapid eye movement, or non-REM is, collectively, sleep stages 1–3. There are distinct electroencephalographic and other characteristics seen in each stage. Unlike REM sleep, there is usually little or no eye movement during this stage.

NSF (formerly National Sanitation Foundation)

A standard by which water filters are judged.

Nuclide

A specific designation of atom characterized by giving the number of protons and neutrons in the nucleus.

Obesity

A medical condition in which the accumulation of excess adipose tissue poses an adverse effect on health.

Occupational Safety and Health Administration (OSHA)

Outlines current indoor air quality guidelines for the workplace.

Octabromodiphenyl Ether

A flame retardant also denoted OctaBDE. Used in conjunction with other chemicals as a flame retardant in the housings of electrical and electronic equipment.

Organ of Corti

The organ of Corti contains the auditory hair cells that respond to the perilymph vibrations and transmit them into electrochemical impulses for the auditory nerve.

Organic Compound

Member of a large class of gaseous, liquid or solid chemical compounds whose molecules contain carbon and hydrogen.

Organochlorine

An organic compound that contains one or more chlorine atoms.

Organotin Compounds

Commonly used as anti-fouling agents, an organic compound with one or more tin atoms in its molecules.

Osteomalacia

Softening of the bones. Known as rickets when observed in children.

Oxidative Phosphorylation Pathway

A pathway in cellular metabolism that re-creates the energy dense molecule adenosine triphosphate.

Oxidative Stress

An insufficient ability to detoxify the products of reactive oxygen species inside one or more cells.

Oxidized

Oxidative rancidity occurs during a free radical process where the double bonds of an unsaturated fat are cleaved in the presence of oxygen, relasing volatile aldehydes and ketones.

Pancreas

A glandular organ that produces several important hormones including insulin, glucagon and digestive enzymes that aid the small intestine in nutrient-absorption.

Paraformaldehyde

A solid thermoplastic form of liquid formaldehyde.

Parasite

An organism that lives in or on another organism (its host) and benefits by deriving nutrients at the host's expense.

Parasympathetic Nervous System

Part of the autonomic nervous system which prepares the body for activities in the absence of stress, such as rest and digestion.

Parkinson's Disease

A progressive disease of the nervous system marked by tremor, muscular rigidity and slow, imprecise movements.

Particle Radiation

High energy particles made of electrons or protons and neutrons which are produced during radioactive decay.

Pathogen

An infectious biological agent such as bacteria, virus and fungus that is capable of causing disease in its host.

Pentabromodiphenyl Ether

A flame retardant also denoted PentaBDE. Most commonly used as a in flexible polyurethane foam and printed circuit boards.

Pentachlorophenol

Ccolorless, crystalline and synthetic compound used in insecticides, fungicides, weed killers and wood preservatives.

Perilymph

The liquid within the inner ear (cochlea).

Period

The duration of one cycle in a wave or wavelength. The reciprocal of frequency

Peripheral Nervous System

Nerve fibers which connect the central nervous system to limbs and organs.

Persistent Bioaccumulative Toxins (PBTS)

A collection of compounds that have high resistance to degradation from abiotic and biotic factors, high mobility in the environment and high toxicity.

Persistent Organic Pollutants (POPS)

Organic compounds that are resistant to environmental degradation through chemical, biological and photolytic processes.

Pesticide Residues

The pesticide that may remain on or in food after they are applied.

Petroleum-based Fertilizers

Petroleum-based synthesized fertilizers were one of the major breakthroughs of the industrial and green revolutions. Today nearly half of all crop yields are directly attributable to synthetic commercial fertilizer. Although these fertilizers can boost yields, over time they lead to lower nutrient content in food, decreased soil biodiversity and are a major source of environmental pollution.

Phagocytic Process

Process of engulfing and ingestion of a foreign particle.

Phase Change

Transformation of matter from one state to another (e.g. melting from solid to liquid or condensing from vapor to liquid). Tremendous change in energy despite no change in temperature.

Phosphogypsum

The byproduct of the processing of phosphate ore; mainly in the production of fertilizers.

Photocatalytic oxidation (PCO)

Achieved when you combine UV light rays with a TiO2-coated filter.

Photopic Sensitivity

The eye's response to brightness using a combination of the M and L cones. Most sensitive to light at 555 nm.

Phthalates

A salt or ester of phthalic acid, most commonly used as plasticizers in PVC.

Pico-

Metric prefix indicating one trillionth of (10¯¹²)

Plasticizers

Added during material production to impart varying degrees of elasticity.

Point Source Pollution

Pollution generated by a single location, such as a power plant or factory.

Polybrominated Diphenyl Ethers (PBDE)

Compounds used as flame retardants in a wide array of products, including building materials, electronics, furnishings, motor vehicles, airplanes, plastics, polyurethane foams and textiles.