Appendix A: Glossary
Acute Exposure |
Single exposure to an environmental condition (not lasting more than a day). Acute exposures contrast with chronic exposures, which are prolonged and repeated. Single exposures still have effects on health. |
Adenosine Triphosphate (ATP) |
A high energy bearing molecule found in all living cells, it converts energy stored in food into chemical energy avilable to the cell. |
Aerobic |
Process taking place with the presence of oxygen. |
Aerosolized |
Act of a substance dispersing into the air. |
Allergic Reaction |
An exaggerated or pathological reaction (sneezing, respiratory irritation, itching or skin rashes) to substances that are without comparable effect on the average individual. |
Allostasis |
Process to achieve homeostasis, a stable physiological state, through physical or physiological alterations. |
Alloy |
A metallic material made of a mixture of two or more metallic elements with nonmetallic elements, usually to impart non-corrosive properties. |
Alpha Radiation |
Ionizing radiation made of a stream of alpha particles (two protons + two neutrons). |
Alveoli |
Small thin-walled air-containing compartments of the lung that are typically arranged in saclike clusters that give the tissue a honeycomb appearance and expand its surface area for the purpose of air exchange. |
Alzheimer's Disease |
A type of dementia marked by the loss of cognitive ability, affecting memory, thinking and behavior generally over a period of 10 to 15 years. |
Amino Acid Metabolism |
The various biochemical processes that relate to protein synthesis from amino acids or protein breakdown into amino acids. |
Amino Acids |
A class of biological compounds that are the second largest (after water) component of cells, muscles and other tissues. |
Anaerobic |
Process taking place without the presence of oxygen |
Anemia |
A reduction in the oxygen carrying component (hemoglobin) of red blood cells with consequent deficiency of oxygen in the blood, leading to weakness and pallor. |
Animal Testing |
Evaluation of toxicity or other effect of a substance or condition through exposure of living animals. A type of in vivo experimentation, as opposed to in vitro. |
Anthropogenic |
Of or originating from human activity. |
Antigen |
Toxin or other foreign substance that induces an immune response in the body, particularly the production of antibodies. |
Antioxidant |
A molecule that inhibits oxidation of other molecules, reducing the production of free radicals, which limit the life of cells. Glutathione, vitamin C, A and E are common and important antioxidants. |
Aplastic Anemia |
Disorder in which bone marrow greatly decreases or stops production of blood cells. |
Apoptosis |
Programmed cell death, usually in response to a disabled poisoned cell. |
Aquifer |
Subterranean source of water. Often tapped for drinking water. |
ASHRAE |
American Society of Heating, Refrigerating and Air-Conditioning Engineers is a global society advancing human well-being through sustainable technology for the built environment. ASHRAE's mission is to advance the arts and sciences of heating, ventilating, air conditioning and refrigerating to serve humanity and promote a sustainable world. |
Assimilation |
The conversion of nutrients into useable form, followed by incorporation into the tissues and organs following digestion. |
Asthma |
Chronic inflammatory disease of the airways. Asthma attacks are often triggered by exposure to allergens, and during an attack the airways spasm, alternatively swelling and narrowing, causing the individual to wheeze or gasp for air. |
Asthma Triggers |
Factors that may instigate asthma in an individual. Common triggers include: allergens, smoke (tobacco and other), air pollution, non selective beta-blockers and sulfite-containing foods. |
Atherosclerosis |
A condition in which arterial walls harden and narrow as the result of accumulating plaque within the inner lining of the artery. |
Auditory Nerve (Cochlear Nerve) |
The auditory nerve, also known as the cochlear nerve, transmits the electrochemical impulses from the organ of Corti to the brain for responses in the body. |
Auditory Ossicles | |
Autism |
A complex disorder with genetic, cognitive and neural components, that is characterized by three major symptoms: impairment in social interaction, impairment in communication and restricted interest and repetitive behavior. |
Autoimmune Response |
Autoimmune responses are a malfunction of the immune system in which an immune response is mounted against healthy tissue within the body. |
Autophagy |
A cellular immunological process responsible for "cleaning" the intracellular space for pathogens and junk molecules. The process is turned on in the absence of macronutrient availability, i.e. times of fasting. |
Axis |
Multiple glands of the endocrine system working together in a specific order. |
Axon |
Fibrous part of a neuron cell. |
Bacteria |
Single-celled organisms, various species of which are involved in fermentation, putrefaction, infectious diseases or nitrogen fixation. Pathogenic bacteria cause disease due to a parasitic relationship with host cells. |
Becquerel |
Unit of radioactivity corresponding to one atomic nucleus disintegration per second. |
Beta Radiation |
Ionizing radiation made of a stream of beta particles (electrons). |
Bile Acids | |
Biologically Active |
A drug or compound that has a beneficial or adverse affect on living matter. |
Bioreactive Form |
Form or state of a substance that governs whether a contaminant will be assimilated into a cell if it is bioavailable. |
Biosynthesis |
An enzyme-catalyzed process in which simple molecules are converted into more complex molecules, often to form proteins, vitamins and immunologically-active compounds. |
Biota |
The combined plant and animal life of a region. |
Bipolar Disorder |
Emotional disorder characterized by mood swings between manic periods of energy and depression. |
Bizngo |
A company that supports the creation of safer chemicals and sustainable materials in a way that supports market transitions to a healthy economy, healthy environment and healthy people. |
Blackbody |
Object which emits the maximum amount of electromagnetic radiation physically possible at a given temperature. |
Blood-Brain Barrier |
Network of blood vessels on the outside of the brain that act as a semi-permeable membrane to prevent toxins from entering the brain. |
Body Burden Testing |
Urine or blood analysis that yields amount of the toxic chemical compounds, elements or their metabolites found in the body. |
Bone Mineral Density |
Parameter of bones indicating the content of minerals such as calcium. |
Bronchopulmonary Aspergillosis |
Aspergillosis is a fungus-induced disease which can take place in the eyes and ears and throughout the respiratory tract; Bronchopulmonary aspergillosis refers to a fungal infection occurring in the lungs. |
Building Envelope |
The separation between the interior and the exterior environments of a building, restricting transfer of air, water, heat, light, noise and creatures. |
Can f 1 |
Common protein produced by dogs that can produce allergic or asthmatic responses in humans. |
Carbon-Hydrogen Bond |
The chemical bond between carbon atom and a hydrogen atom. |
Celiac Disease |
An autoimmune disorder of the small intestine that occurs in those that are genetically predisposed. |
Cell Membrane |
The layer of a cell that separates the interior from the exterior, composed primarily of a lipid bilayer with embeded proteins, carbohydrates and other compounds. |
Cellular Structures |
The total type and arrangement of components in a cell, including complex system of metabolic reaction pathways, protein synthesis and a membrane, that vary depending on species and specialized function. |
Central Nervous System |
Brain and spinal cord. |
Central Nervous System Messengers |
Chemical messengers that pass messages between nerve cells. |
Chicken Pox |
A common and extremely infectious viral childhood disease that also affects adults on occasion. It produces an itchy, blistery rash that typically lasts about a week and is sometimes accompanied by a fever or other symptoms. |
Cholera |
An acute infectious disease of the small intestine, caused by water or food contaminated with bacteria and characterized by profuse watery diarrhea, vomiting, muscle cramps and severe dehydration. |
Chronic Diseases |
Any disease that is persistent or has long-lasting health effects. |
Chronic Exposure |
Repeated, continuous exposure to a substance or condition over an extended period from several years to a lifetime. |
Chrysotile Asbestos |
The most commonly used type of asbsestos. It is generally preferred over other types because of its flexibility and being able to be spun and woven into fabrics. |
Circadian Rhythms |
Internal clock that keeps the body's hormones and bodily processes on a roughly 24-hour cycle, even in continuous darkness. |
Citrate Synthase |
This enzyme is indicative of a tissue's power to use oxygen. It is often measured as a quantitative marker for the presence of intact mitochondria. Exercise can increase expression of citrate synthase. |
Clean Air Act |
Federal law designed to control air pollution on a national level. Requires the EPA to develop, set standards and enforce regulations that protect the public from airborne contaminants known to be hazardous to human health. |
Clean Water Act |
Law passed in 1972 to broadly regulate water pollution by imposing controls on pollutant discharge points and keeping track of water quality; In 1987, the government updated the act by including provisions for storm sewers and similar broad routes of pollution. |
Clinical Research |
Testing conducted using consenting human subjects that tests the effectiveness and safety of a treatment, a diagnostic tool or chemical. Usually the last stage of testing before approval. |
Cochlea |
A bony, fluid filled, snail shell-like structure composed of three chambers (two empty chambers and third for the organ of Corti) that make up the inner ear. It transmits sound pressure waves into electrochemical impulses for the auditory nerve. The cochlea houses the organ of Corti, auditory nerve and perilymph fluid. |
Coenzyme |
A class of chemicals that are required for certain enzymes to function. |
Cognitive Function |
Cognition is the scientific term for "the process of thought", cognitive function (or cognition) describes the process by which one becomes aware of, perceives or comprehends ideas. It involves all aspects of perception, thinking, reasoning and remembering. |
Cognitive Impairment |
An inclusive term to describe any feature that acts as a barrier to the cognition process, and can be used to describe various types of deficits, whether global, as with mental retardation or specific as when relating to learning disorders. |
Collaboration Zone |
A physical area within a building that encourages group interplay and discussion though its strategic layout and design. |
Collagen |
A group of proteins found in connective tissue including tendons, ligaments, skin, bone, blood vessels and intervertebral discs. |
Collagen Repair |
Repair of the main protein constituent of skin that provides strength, flexibility and resilience. |
Colorectal Cancer |
Cancer from uncontrolled cell growth in the colon or rectum (parts of the large intestine). |
Commodity Crops |
A group of relatively inexepensive, nonperishable, storable plants that are grown in relatively large volume and intensity. Corn, soybean, wheat and rice are the largest commodity crops. |
Complementary Colors |
Two colors which, when combined, produce white light. |
Conduction |
Heat transfer through physical contact with another object. |
Cone Cells |
Photosensitive cells in the eye used to differentiate colors and brightness in moderate and high levels of illumination. |
Congeners |
A class of related compounds, similar in structure and chemical properties. |
Conjunctivitis |
Inflammation of the conjunctiva, the lining on the inside of the eyelids and covering the white of the eyes. |
Consumer Product Safety Commission (CPSC) |
An independent agency of the United States government. Regulates the sale and manufacture of more than 15,000 different consumer products. |
Contaminate Candidate List (CCL) |
List of contaminants created by the EPA that are known to occur in drinking water and may require regulation under the Safe Drinking Water Act (SDWA), based on research from the scientific community, but are not presently subject to regulation standards. |
Convection |
Heat transfer through movement of a fluid over a solid. |
Core Body Temperature (CBT) |
Temperature of an organism far with the body, such as in internal organs. |
Coronary Heart Disease |
A heart condition caused by reduced blood flow through the coronary arteries to the heart muscle, typically resulting in chest pain or heart damage. |
Crohn's Disease |
Type of inflammatory bowel disease that may affect any part of the gastrointestinal tract. |
Cryptosporidium |
Protozoa that can cause diarrhea and other digestive problems; Somewhat resistant to chlorine and chloramine. |
Cubic Foot Per Minute (CFM) |
A unit of airflow that indicates how many cubic feet of air pass by a stationary point in one minute under standard conditions of temperature, pressure and humidity. |
Culturable Mold |
Culturable mold can be defined as mold that is alive, and will therefore grow in a culture sample, as opposed to non-culturable mold that is dead or dormant and would go undetected with culture sampling. |
Curie |
Unit of radioactivity corresponding to 37 billion atomic nucleus disintegration per second. |
Dental Fluorosis |
An aesthetic mottling of the teeth caused by excessive ingestion of fluoride. |
Depressed Mood |
Although a number of psychiatric syndromes feature depressed mood as a main symptom, depressed mood is not necessarily a psychiatric disorder. Depressed mood may be a normal reaction to certain life events, a symptom of some medical conditions or a side effect of some drugs or medical treatments. |
Dermal Integrity |
Integrity of layer of the skin located below the upper most layer, containing nerve endings, sweat and oil glands, as well as blood and lymph vessels. |
Dermis |
The deepest or innermost layer of the two main layers that make up the skin containing blood and lymph vessels, hair follicles and glands. |
Developmental Toxins |
A subgroup of reproductive toxins that cause malformations of an embryo or fetus. Effects may occur from conception to sexual maturity and include spontaneous abortion, structural or functional defects, low birth weight or effects that may appear later in life. |
Diabetes |
A group of diseases that impact the metabolism due to insufficient insulin production (Type 1) and/or high insulin resistance (Type 2), and a leading cause of death. Results in poor blood sugar control, frequent urination, increased thirst, increased hunger and other symptoms. |
Diabetic Ketoacidosis | |
Diesel Particulate Matter (DPM) |
Particulate component of diesel exhaust, which includes diesel soot and aerosols such as ash particulates, metallic abrasion particles, sulfates and silicates. |
Dietary Minerals |
Inorganic nutrients required by living organisms for optimal functioning other than those elements present in common organic molecules: carbon, hydrogen, nitrogen and oxygen. |
Dioxins |
A highly toxic class of chemicals contaminants formed during combustion processes and some industrial processes. |